DOXYCYCLIN

Main indication,

- Chlamidia/gono

- Sinusitis (with diclofenac)

- chronic bronchitis

Dose

100mgr x 2

Maximal dose is 600 mg per day

No dosage reduction in renal impairment.

 

Possible side/adverse effect

- gastro-intestinal dyscomfort, abdominal pain, nausea, vomiting... (reduced with food)

- Diarrhea

- photosensitivity increased sensitivity of skin to sunlight

- hepatotoxicity has occurred

 

Drug interactions

Antacids or Calcium supplements or Iron supplements or Magnesium... concurrent use may result in decreased absorption. patients should be advised not to take these medications within 1 to 3 hours of doxy absorption

Barbiturates or Phenytoin concurrent use with doxycycline may result in decreased doxycycline serum concentrations adjustment of doxycycline dosage may be necessary

Penicillin, amoxy, cloxa... since bacteriostatic drugs may interfere with the bactericidal effect of penicillins in the treatment of meningitis or in other situations where a rapid bactericidal effect is necessary, concurrent therapy is not recommended

 

Other informations

Store below 40 °C , preferably between 15 and 30 °C Store in a tight, light-resistant container.