Cloxacillin injectable

For cloxacillin per os, click here

Main indication,

- skin bacterial infection (yellow pus...) when genta in not available or not indicated (kidney failure...)

- Skin bacterial secondary infection (on scabies, psoriasis, zoster...)

- With ampi for septicemia when genta in not available or not indicated (kidney failure...)

- osteomyelitis, cellulitis....

Dose

- 500 mg x 4 (per os or injection as well)

- Maximum for adult : 6 grams a day.

To prepare for intramuscular injection, add 1.7 mL of sterile water for injection to each 500 mg and shake to dissolve. 101

To prepare for intravenous injection, add 4.8 mL of sterile water for injection to each 500 mg, and shake to dissolve.

For direct intravenous use, the resulting solution should be administered slowly over a 2- to 4-minute period.

Drug interactions

- Extemporaneous admixtures of cloxa and aminoglycosides may result in substantial mutual inactivation. If these groups of antibacterials are administered concurrently, they should be administered in separate sites at least 1 hour apart. Do not mix them in the same intravenous bag, bottle, or tubing.

Possible side/adverse effect

- Anaphylactic!!! (Cross allergy with other drugs of same family: pen, amoxy...)

- Exfoliative dermatitis (red, scaly skin); serum sickness-like reactions (skin rash; joint pain; fever); skin rash, hives, or itching

Contraindications

-

Other informations

- injectable: prior to reconstitution, store between 15 and 30 °C Stability: after reconstitution, solutions retain their potency for 24 hours at controlled room temperature (25 °C ), or 72 hours if refrigerated.